“A Lassa fever prevention intervention that targets the environmental (e.g. improved household sanitation) and animal (e.g. rodent removal) domains may show promise, but omission of the human domain (e.g. education of nurses on disposal of contaminated material in hospitals) may result in a missed opportunity to achieve optimum results. At worst, siloed approaches may lead to unforeseen detrimental effects. In the Lassa fever example, removal of rodent populations may result in increased malnutrition among humans if rodents were a significant direct or indirect (i.e. prey for larger food source animals) source of protein for families living in affected communities.” Extracted from A framework for One Health research.⁷